Automated Headspace Analysis

Driven by continuous innovation, WILCO has continuously developed the HSA technology since 2003 when the first inline HSA system was installed. With the latest generation of lasers, a new milestone in terms of speed and detection limits has been reached.

SPECTRA HSX 100

The SPECTRA HSX 100 impresses with its highly sensitive laser system and the flexibility to be configured for individual requirements on a small footprint. The compact inspection platform is developed for non-destructive Headspace Analysis of pharmaceutical packages with modified headspace conditions.

Sensitive

The SPECTRA HSX uses WILCOs 4th generation laser heads with industry-leading sensitivity

Compact

The SPECTRA HSX 100 has a small footprint and can be used in small labs and production areas.

Intuitive

The MAVIS operation system allows an intuitive machine operation and complies with 21 CFR Part 11.

Multiple laserheads

Single or dual lasers can be integrated for sensing of one or multiple gases.

The SPECTRA HSX 100 is a mobile and very compact inspection platform developed for non-destructive Headspace Analysis of pharmaceutical packages such as vials or ampoules. Glass or plastic containers from 2 ml up to 100 ml can be inspected at a speed of up to 100 test samples per minute. The laser head features an automatic height adjustment for an easy format changeover.

Inspection of multiple gases

With our newest laser generation we reach industry leading sensitivity. Optionally, two different laser heads can be integrated to check for both the partial pressure of oxygen or carbon dioxide and the total pressure inside the test sample. 

Intuitive operation

The SPECTRA HSX is eqquiped with our MAVIS user interface. The operator is guided through the inspection process and informed visually about the operation. 

Features

  • Applicable for vials and ampoules
  • Up to 2 laser heads
  • Latest generation of HSA Lasers
  • Customizable interface by means of widgets
  • Enhanced recipe management system
  • Enhanced connectivity, reporting and backup functions
  • Integrated online verification system
  • Compact and mobile design
  • Machine design according GMP guidelines
  • In accordance with UL requirements
  • Test method preferred according USP1207
  • Automatic retest function for uninspected containers
  • Automatic height adjustment of laser

SPECTRA HSX 300

The verification of quality relevant attributes of the headspace conditions e.g. in lyophilized and liquid filled vials, requires non-destructive and robust inspection technologies. The SPECTRA HSX platform impresses with its highly sensitive laser system and the flexibility to be configured for individual requirements.

WILCO automated CCI tester for Headspace Analysis

Latest generation of HSA lasers

With our latest generation of Headspace Analysis heads new mile stones in terms of sensitivity and acqusition time are set.

Online calibration system

To verfify the correct calibration of the HSA system during multiple-hour production runs, an online calibration system is integrated and ensures maximum process reliability.

Smooth container transport

The transport system is designed to minimize pressure and friction on the containers to reduce the risk of scratches or other damage.

The SPECTRA HSX 300 is a compact inspection platform developed for non-destructive Headspace Analysis of pharmaceutical packages with modified headspace conditions. Due to the continuous developments of the laser system it can be used for the highest requirements and with the flexibilty of integrating additional inspection technologies. The system is capable of testing 2ml vials to LVP bottles or other packaging types. Depending on the given conditions and requirements, up to two test heads can be integrated. By increasing the number of test heads either the throughput or the sensitiviy can be improved.
 

Inspection of multiple gases

Optionally, two different laser heads can be integrated to check for both the partial pressure of oxygen or carbon dioxide and the total pressure inside the test sample. Additionally, a NIR spectroscopy module for moisture detection in lyophilizates or barcode readers for container identification can be integrated.

Features

  • Throughput up to 300 pcs/min
  • 2ml up to 100 ml containers
  • Non-destructive head space analysis of vials, syringes, ampoules
  • Deterministic CCIT method preferred acc. USP<1207>
  • Applicable for glass and plastic containers
  • Simple format changeover
  • Design according GMP guidelines
  • Data Handling in compliance with 21 CFR part 11
  • Reliable product handling
  • Toolless format changeover
  • Optional integration of visual inspection systems
  • Optional integration of 2D DataMatrix Code reader
  • Optional integration of NIR Module for residual moisture and lyo defects

SPECTRA HSX 500

The verification of quality relevant attributes of the headspace conditions e.g. in lyophilized and liquid filled vials, requires non-destructive and robust inspection technologies. The SPECTRA HSX 500 platform is designed to meet the highest requirements in terms of sensitivity and throughput for automated Headspace Analysis.

WILCO automated Headspace Analyzer

Latest generation of HSA lasers

With our latest Head Space Analysis generation, we are setting new milestones in terms of sensitivity and inspection speed.

Integrated online calibration system

To verify the correct calibration of the HSA system during multiple-hour production runs, an online calibration tool was integrated to ensure maximum process reliability.

Integration of multiple test heads

The SPECTRA HSX 500 platform can accommodate up to 10 test heads providing the highest sensititity.

The SPECTRA HSX 500 is an inspection platform developed for non-destructive Headspace Analysis for pharmaceutical packages with modified headspace conditions. Headspace Analysis may be used for nitrogen purging efficiency, vacuum verification or container closure integrity testing (CCIT).

Due to the continuous developments of the laser headspace system the SPECTRA HSX 500 qualifies for the highest requirements and provides the option to add further inspection technologies. Depending on the given conditions, up to ten test heads can be integrated. By increasing the number of test heads both the throughput and the sensitivity are improved.

Integration of additional inspection methods for vials

The integration of NIR spectroscopy modules for moisture detection in lyophilizates or barcode readers for container identification is optional. The combination with other inspection platforms such as the automated visual inspection platform is also possible.

Features

  • Up to 500/min
  • 2ml up to 100 ml containers
  • Non-destructive head space analysis of vials, syringes, ampoules
  • Deterministic test method preferred acc. USP1207
  • Applicable for glass and plastic containers
  • Applicable for liquid, lyophilized and solid products
  • Designed according to GMP guidelines
  • Data Handling in compliance with 21 CFR part 11
  • Reliable product handling
  • Toolless format changeover
  • Optional integration of visual inspection systems
  • Optional integration of 2D DataMatrix Code reader
  • Optional integration of NIR Module for residual moisture and lyo defects